March Madness Picks Against the Spread for Saturday, April 4

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The 2026 Men’s Final Four goes down tonight at Lucas Oil Stadium in Indianapolis.

The first matchup features the No. 3 Illinois Fighting Illini and the No. 2 UConn Huskies, followed by the heavyweight showdown of the No. 1 Michigan Wolverines and the No. 1 Arizona Wildcats.

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Read on for my March Madness picks against the spread for both Final Four games on April 4, and see why I have Illinois advancing to its second-ever National Championship Game.

March Madness against the spread picks on Saturday, April 4

Matchup

Pick

Illinois
vs
UConn

-2

Arizona
vs
Michigan

+1.5

Lines courtesy of bet365.

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Expert March Madness Final Four ATS picks for Saturday

No. 3 Illinois vs No. 2 UConn: Illinois -2 (-110)

The Illinois Fighting Illini are the better team, and are still favored despite a significant Dan Hurley tax baked into this line.

Little can be taken away from the regular season meeting between these programs on November 28, so instead, let’s breakdown the matchup.

Illinois has more playmakers and shot-makers offensively, canning 10.7 3-pointers per game and shooting 78% from the stripe. The UConn Huskies are hitting just 27.5% from beyond the arc since March 1 and are poor shooters at the foul line (71.9%).

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Much has been made about Illinois’ defense, which was perceived to be a weakness heading into the NCAA Tournament, but that was more reputation and vibes-based thinking than reality.

Illinois…

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Publish date : 2026-04-04 12:13:00

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