Top 10 March Madness Upsets of All Time: 2026 Bracket Buster Guide

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If there’s one thing March Madness is known for, it’s the upsets.

2025 saw just three “upsets” in Round 1 — an 11-seed and two 12-seeds — while two years prior saw seven upsets… and in 2023 we have all four No. 1 seeds eliminated before the Elite 8 for the first time in NCAA Tournament history.

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Upsets are a huge reason basketball fans love betting on March Madness odds, and you’ll need to select a few if you plan on winning your bracket contest. With the 2026 tournament about to begin, we recount the biggest March Madness upsets ever — plus some tips on how to identify future possible upsets so you can make the best March Madness bets.

Top 10 March Madness upsets of all time

The 10 biggest March Madness upsets since 2000:

Ranking the Greatest Bracket Busters in History

Honorable Mention: Georgetown vs. Ohio (+13.5) 2010

That the 14th-seeded Bobcats notched their first NCAA Tournament win in 27 years — at the expense of Georgetown — is shocking enough, but Ohio was somewhat lucky to even be in the tournament.

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It was just the ninth seed in the MAC Tournament, but made an incredible run to the Big Dance and carried that momentum into the opening round, jumping out to a 12-point lead at halftime, holding a 19-point lead in the second half, and holding on for a comfortable 97-83 victory.

Honorable Mention: Georgetown vs. Florida Gulf Coast (+13.5) 2013

The Hoyas didn’t learn their lesson from three years earlier and found themselves in a pace mismatch with one of the most exciting teams in college hoops that season. The No. 15 Eagles lived up to their nickname “Dunk City” and wore the wheels off No. 2 Georgetown with 54 points in the second half.

Honorable Mention: Wichita State vs. Marshall (+13.5) 2018

The No. 4 Shockers were established March Madness mavens at this point, garnering a lofty 13.5-point spread versus No. 13 Marshall. The Thundering…

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Publish date : 2026-03-16 19:09:00

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