Rockets vs. 76ers predictions: Odds, recent stats, trends and best bets for January 22

Winners of three straight, Kevin Durant and the Houston Rockets (26-15) are in the City of Brotherly Love tonight to take on Tyrese Maxey and the Philadelphia 76ers (23-19). Now sitting second in the Southwest Division – just 2.5 games behind Victor Wembanyama and the San Antonio Spurs, the Rockets take the court against a 76ers’ team looking to get right after losing three of its last four.

Kevin Durant and his 25.9 points per game is of course the headliner for the Rockets but all of a sudden sophomore guard Reed Shepherd has stepped up during the winning streak scoring 14, 11, and 21 points shooting 11-23 (47.8%) from beyond the arc. Philadelphia lost 116-110 at home to Devin Booker and the Suns Tuesday night. Rookie V.J. Edgecombe led Philly with 25 points in the loss.

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Paul George (knee) and Joel Embiid (ankle) did not play against the Suns. While neither is the player or specifically the defender they were in their respective primes, their size is needed tonight to compete against a Houston team that dominates the boards. Led by Alperen Sengun (9.3 RPG), the Rockets average 49 rebounds per game – 16.1 on the offensive end – and most importantly, are outrebounding their opponents overall by an average of 6.6 boards per game.

This is the first of two meetings this season between the two teams.

Lets take a closer look at the matchup and take into consideration lineups, injuries, and other factors affecting the line and total.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds courtesy of DraftKings recent team performance, player stats, and of course, our predictions, picks best bets for the game from our modeling tools and staff of experts.

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Game Details and How to Watch Live: Rockets at 76ers

Date: Thursday, January 22, 2026

Site: Xfinity Mobile Arena